[PDF][PDF] Cerebral Diffusion and T2: MRI Predictors of Acute Mountain Sickness during Sustained High-Altitude Hypoxia
JS Hunt Jr, RJ Theilmann, ZM Smith… - Journal of Cerebral …, 2013 - journals.sagepub.com
Diffusion magnetic resonance imaging (MRI) provides a sensitive indicator of cerebral
hypoxia. We investigated if apparent diffusion coefficient (ADC) and transverse relaxation
(T2) predict symptoms of acute mountain sickness (AMS), or merely indicate the AMS
phenotype irrespective of symptoms. Fourteen normal subjects were studied in two groups;
unambiguous AMS and no-AMS at 3,800 m altitude (intermediate AMS scores were
excluded). T2 relaxation was estimated from a T2 index of T2-weighted signal normalized by …
hypoxia. We investigated if apparent diffusion coefficient (ADC) and transverse relaxation
(T2) predict symptoms of acute mountain sickness (AMS), or merely indicate the AMS
phenotype irrespective of symptoms. Fourteen normal subjects were studied in two groups;
unambiguous AMS and no-AMS at 3,800 m altitude (intermediate AMS scores were
excluded). T2 relaxation was estimated from a T2 index of T2-weighted signal normalized by …
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